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Diagnostic hysteroscopy

After the menopause, any bleeding needs checking

Bleeding after the menopause, even slight and only once, should always be checked. The cause is usually benign, such as endometrial atrophy or a polyp, but endometrial cancer has to be ruled out. Ultrasound guides the next step; hysteroscopy with targeted biopsy gives the answer.

Hysteroscopic view: atrophic endometrium after the menopause (illustration)

Hysteroscopic view · illustration

Key points

  • Any bleeding a year or more after the last period should be investigated.
  • Most common causes: endometrial atrophy and polyps; cancer is found in about 9% of cases.
  • An endometrium of 4 mm or less on ultrasound is very reassuring.
  • Above that, or if bleeding persists: hysteroscopy with targeted biopsy.
Contents
  1. Why must any bleeding be checked?
  2. What are the causes?
  3. Which tests?
  4. Hysteroscopy after the menopause
  5. What if there is no bleeding?
  6. Frequently asked questions
  7. References

Why must any bleeding be checked?

After the menopause the endometrium should no longer bleed, so bleeding is always a signal. A meta-analysis of more than 40,000 women found endometrial cancer in about 9% of those with postmenopausal bleeding. Conversely, nine times out of ten the cause is benign.

Bleeding is the first sign of most endometrial cancers: investigating early means diagnosis at an early stage, when cure is the rule.

Frontal section of the uterus, tubes and ovaries Uterine fundusFallopian tubeOvary Myometrium Endometrium Isthmus Cervical canal Vagina Tubal openings Pedunculated polyp Submucosal fibroid Uterine septum Adhesions Caesarean scar niche(anterior wall) Retained tissue Displaced IUD Endometrium removedor destroyed Thin endometrium(atrophy) Endometrial tumourinvading the myometrium
Hysteroscopic view: atrophic endometrium after the menopause (illustration)

Hysteroscopic view · illustration

Menopause: what hysteroscopy showsLeft, the finding placed in a frontal section of the uterus; right, how it looks on screen during the examination.Diagram: Hystéroscopie Paris · View: Guillaume Blanchet

What are the causes?

CauseWhat to know
Endometrial atrophyMost common cause: a thin, fragile lining that bleeds easily
PolypCommon; removed and analysed after the menopause
HyperplasiaThickened endometrium; the atypical form is precancerous
Endometrial cancerAbout 9% of postmenopausal bleeding
Hormone therapyBleeding possible in the first months; investigate if it persists

Which tests?

Transvaginal ultrasound measures endometrial thickness. A thickness of 4 mm or less is very reassuring in a woman with postmenopausal bleeding: the risk of cancer is then very low. Above that, or if the endometrium is poorly seen, tissue sampling is needed.

Pipelle biopsy, done in clinic, samples the endometrium blindly. Hysteroscopy shows the cavity and samples the exact suspicious area: it is the test of choice when a focal lesion is suspected, or when bleeding continues despite a normal biopsy.

Female pelvis, midsagittal section — Bladder, uterus and rectum in sagittal section: the uterine cavity is a slit between two walls.
Female pelvis, midsagittal sectionBladder, uterus and rectum in sagittal section: the uterine cavity is a slit between two walls.Illustration: Guillaume Blanchet · © Dr Olivier Kadoch

Hysteroscopy after the menopause

The examination is the same as before the menopause: in the consulting room, using a fine telescope and a speculum removed quickly. The cervix is sometimes narrowed by atrophy; local oestrogen for a few days beforehand can make entry easier. If the cervix stays closed, hysteroscopy is done in theatre under anaesthesia.

A polyp is removed at the same time and analysed. A suspicious area is biopsied under direct vision; results take about a week.

What if there is no bleeding?

A thick endometrium found by chance on ultrasound, with no bleeding, does not always require hysteroscopy: the threshold for investigation depends on thickness, appearance and your risk factors. On tamoxifen, routine ultrasound screening is not recommended without bleeding; any bleeding, however, must be investigated.

Frequently asked questions

Is a single episode of light bleeding after the menopause serious?

Usually not, but it must always be investigated, because it is the first sign of most endometrial cancers.

What does a 4 mm endometrium mean?

In a woman with postmenopausal bleeding, an endometrium of 4 mm or less on ultrasound is very reassuring. Above that, a sample is needed.

Is hysteroscopy harder after the menopause?

Sometimes, because the cervix may be narrowed. Local oestrogen helps; otherwise the examination is done under anaesthesia.

Can my hormone therapy cause bleeding?

Yes, especially in the first months. Bleeding that persists beyond six months or starts later should be investigated.

References

Clarke MA et al. · 2018Association of endometrial cancer risk with postmenopausal bleeding in women: a systematic review and meta-analysisJAMA Intern Med
ACOG · Committee Opinion 734 · 2018The role of transvaginal ultrasonography in evaluating the endometrium of women with postmenopausal bleedingObstet Gynecol
Concin N et al. · ESGO/ESTRO/ESP 2021Guidelines for the management of patients with endometrial carcinomaInt J Gynecol Cancer
CNGOF · 2013Recommandations pour la pratique clinique : hystéroscopieJ Gynecol Obstet Biol Reprod

Written and reviewed by Dr Olivier Kadoch · 18 October 2026

This page is for information; it does not replace a consultation. Each situation is discussed individually.

A 10-minute examination for a clear answer.

Diagnostic hysteroscopy in the consulting room, without anaesthesia, in Paris 16th and 5th.